Directory of Peptide API Manufacturing Plants

Wuhan Newtop Biotech Co., Ltd., located in Wuhan, Hubei, is a pharmaceutical manufacturing enterprise integrating R&D, production, sales and service, focusing on organic chemistry and pharmaceutical chemistry, with its own R&D center and laboratory. The company mainly focuses on polypeptides and pharmaceutical raw materials, including Semaglutide, Tirzepatide, Retatrutide, Cagrilintide, GHK-Cu, Melanotan, Thymosin alpha-1, LL-37, Selank, Epitalon, etc., and provides peptide freeze-dried powder and raw materials. With peptide synthesis, purification and active ingredient separation capabilities, the production system has obtained GMP, ISO 9001, HSE and other quality certifications, and has a D-level (ISO 8)/C-level (ISO 7) clean workshop; products are mainly exported to Europe, the United Kingdom, the United States, Canada, Australia and other countries and regions.

Chongqing Zhixia Chemical Co., Ltd. (related to Nanjing Chenruisheng Biomedical Technology) was established in September 2023. It is a small and micro enterprise, mainly engaged in the research and development and supply of polypeptide GLP-1 raw materials, representing products including Semaglutide, Tirzepatide and other polypeptide raw materials. The business model is factory, customization and service, and the products are mostly marked as "for scientific research or export only". The company announced a registered capital of 500,000 yuan, 10–50 employees, and an annual turnover of about 3-5 million yuan. The contact information is shared with Nanjing Chen Ruisheng (the same phone/email address), and is positioned as a peptide small molecule GLP-1 raw material supplier for the global scientific research and export market.

ZhuoShang Bio/ExcelBio is a GMP-certified nutraceutical manufacturer founded in 2013, located in Luoyang, Henan Province, focusing on providing one-stop OEM/ODM solutions for global brands; with 30,000 m ² of FDA-registered factories (10 production lines with an annual output value of more than $100 million), supporting a minimum order of 500 pieces. Main proteins, polypeptides and custom peptides (such as GHK-Cu, GHK-Cu powder, etc.), protein powder, gummies, capsules, beverages, etc., provide full link services from R&D, procurement, production to logistics, and hold GMP, FDA, COA, HACCP, Halal and other certifications. Note: The company's self-built official website has not been retrieved. This profile is from the Made-in-China corporate store, which is a third-party trading platform information, for reference only.

Sichuan Ampelbo Biotechnology Co., Ltd. (Chengdu Boke Pharmaceutical Technology Co., Ltd., Chengdu) is a professional R&D, production and sales of amino acid derivatives (amino alcohols, amino aldehydes, N-methyl amino acids, amino acid tert-butyl esters, Boc/Fmoc/Cbz protected amino acids, benzyl esters, amino acid amides, etc.). It also provides polypeptides, piperidine derivatives and chiral amine series products. It can provide domestic and foreign customers with high-quality pharmaceutical intermediates and fine chemicals from grams, kilograms to tons. Its products are exported to Europe and North America. It is a small high-tech/trade-oriented enterprise (with a staff size of about 8–50 people). The polypeptide is one of its product lines, with a partial amino acid protecting group and a polypeptide side chain/intermediate direction.

Founded in 2018, it focuses on the European, American, Indian, and African markets, and supports Paypal, Western Union, and Bitcoin payments.

Shanghai Bootech Biotechnology Co., Ltd. (registered as "Bootech" on the official website, and the user is recorded as "Botech") was founded in 2003 and is a technology company specializing in the synthesis of peptides and the sale of supporting reagents. The company relies on and absorbs international advanced technology, has advanced synthesis and purification equipment, and develops a complete set of peptide synthesis routes, which can provide peptide products of various sizes and requirements (mg to kg). Each polypeptide is accompanied by HPLC analysis and mass spectrometry identification report. Provided by a number of senior researchers/professors to provide process guidance, long-term cooperation with domestic and foreign pharmaceutical companies and scientific research institutions to provide high-quality peptides and peptide raw materials products at a price advantage.

Shanghai QYAOBIO Co., Ltd. (ChinaPeptides/QYAOBIO), founded in October 2008, is a technology-based enterprise focusing on peptide synthesis, protein expression, and antibody preparation. In China, peptide solid phase synthesis (SPPs) technology was adopted earlier. The company maturely mastered 300 + peptide special modification core technologies, and has branches and scientific research laboratories in Suzhou, Wuhan, and Ezhou; cumulatively serving more than 50,000 customers worldwide, covering more than 50 countries and China's Hong Kong, Macao, and Taiwan regions, of which more than 90% are biomedical research institutions and pharmaceutical companies such as universities, hospitals, laboratories, and research institutes. Has passed ISO 9001: 2015 quality system certification, > 99% peptide synthesis success rate, provide HPLC/MS report and optional endotoxin/salt type test, as soon as 3 days delivery; core business is peptide synthesis, protein expression and antibody preparation.

Focus on overseas Biohacking channels, mature composite peptide kits

Nanjing Yuanpeptide Biotechnology Co., Ltd. (Yuanpeptide Biotechnology) was established in 2018 and is located in the Biomedical Valley/Zhongdan Ecological Life Science Industrial Park in Jiangbei New District of Nanjing. It is a science and technology-based small and medium-sized enterprise (selected as a science and technology-based small and medium-sized enterprise in Jiangsu Province in 2025) that focuses on the synthesis of scientific research peptides and customized services. The company has 46 employees, an independent research and development center and 900 square meters of sterile laboratory, 4 standardized peptide production lines, equipped with Waters LC-MS/MS, UPLC, automatic purification system, automatic lyophilization system and other precision instruments, with a peak monthly production capacity of about 3000 peptides. Stable synthesis of conventional linear peptides and 60 amino acid long peptides, 100 amino acid super long peptides, specializing in polydithiocyclic peptides, head and tail closed-loop peptides, book peptides, highly hydrophobic membrane penetrating peptides, D-type amino acid peptides, glycopeptides, lipopeptides and other complex structures; modified types cover phosphorylation, sulfonation, methylation, acetylation, pegylation, biotin labels, a variety of fluorescent labels (FITC/Cy series), isotope labels (13c/15N), protein cross-linking and more than 300 kinds. Service ranges from milligrams to kilograms, and long-term cooperation with universities and medical institutions such as Nanjing University, Fudan, Shanghai Jiaotong University, and West China Hospital.

Hefei Peptide Library Biotechnology Co., Ltd. (Taikubio) is a high-tech enterprise committed to peptide synthesis research and peptide custom synthesis. The core team has a background in the chemical industry at home and abroad and rich R&D and management experience. The company has 1500 square meters of office/experimental space, equipped with precision instruments such as Waters LC-MS/MS, UPLC, automatic purifier, Shimadzu LCMS, and automatic lyophilization system; thousands of catalog peptides such as polypeptides/pet probe precursors are available in stock, and more than 400 kinds of modification and drug coupling technology routes are accumulated, which can undertake milligram to kilogram level production, covering the comprehensive needs of scientific research and customization and from small-scale trials, pilot trials to large-scale production. Mainly engaged in peptide API intermediates, cosmetic peptides, customized peptides, and HPLC purification and bioassay services; can be customized to produce pet probe precursors (FAPI, PSMA, polypeptides, NEB, etc.) and related intermediates. It has established cooperation with universities such as Peking University, Tsinghua University, Zhejiang University and foreign pharmaceutical companies.

Founded in 2014, Hangzhou Go Top Peptide Co., Ltd. (Go Top Peptide) is a national high-tech enterprise focusing on the R&D and production of polypeptides and related derivatives. It is the governing unit of the polypeptide branch of the China Biochemical Pharmaceutical Industry Association. The company has more than 4,000 square meters of polypeptide research and development center in Hangzhou, and has established two commercial polypeptide production bases in Shangyu and Anji, Zhejiang. It has a number of polypeptide production lines, large-scale polypeptide synthesis equipment, imported HPLC analysis and preparation equipment, and is equipped with a GMP standard clean laboratory. It has passed ISO9001: 2015 quality management system certification. Provides peptide customization, modification, catalogue peptides and scientific/pharmaceutical peptide products.