Directory of Peptide API Manufacturing Plants

Wuhan Newtop Biotech Co., Ltd., located in Wuhan, Hubei, is a pharmaceutical manufacturing enterprise integrating R&D, production, sales and service, focusing on organic chemistry and pharmaceutical chemistry, with its own R&D center and laboratory. The company mainly focuses on polypeptides and pharmaceutical raw materials, including Semaglutide, Tirzepatide, Retatrutide, Cagrilintide, GHK-Cu, Melanotan, Thymosin alpha-1, LL-37, Selank, Epitalon, etc., and provides peptide freeze-dried powder and raw materials. With peptide synthesis, purification and active ingredient separation capabilities, the production system has obtained GMP, ISO 9001, HSE and other quality certifications, and has a D-level (ISO 8)/C-level (ISO 7) clean workshop; products are mainly exported to Europe, the United Kingdom, the United States, Canada, Australia and other countries and regions.

Wuhan Vanz Pharm Inc.), located in Wuhan, Hubei Province, was established in 2011 (some B2B files are recorded as 2016). It is a API (API), pharmaceutical intermediates, fine chemicals, peptides and food additives that integrate R&D, production and sales. Its products are sold worldwide. The company has a R&D center of about 1000 square meters in Wuhan (including multiple synthesis laboratories, pilot amplification laboratories and analytical laboratories). The manufacturing base is equipped with 100L-5000L reactors, which can provide one-stop services from R&D to commercial production. With long-term cooperation from Shanghai Institute of Organic Chemistry and Wuhan University, it has completed more than 20 APIs and intermediates R&D. Business covers custom synthesis (CDMO/CMC orientation), API contract production, quality control and regulatory consulting. Note: The company uses small molecule APIs/intermediates and custom synthesis as its core business, and peptides is only one of its product categories, not a dedicated peptide API factory.

Wuhan Hubei Huntide Biotech Co., Ltd.), an innovative manufacturer of small molecule peptides under Jetide Health, is located in Wuhan Optical Valley Biocity and has a production base built according to industrial standards in Xintan Industrial Park, Wuhan Economic Development Zone. The company's team has an average of more than 10 years of experience in the pharmaceutical/biological field. It has built a peptide R&D center of about 800 ㎡ and a cGMP standard multi-function workshop, focusing on the synthesis of small peptides with 2–6 amino acids. The core technologies include liquid phase, solid phase, fragment and enzyme catalytic synthesis (especially liquid phase synthesis), and provide modification services such as C-terminal/N-terminal modification, disulfide bond/amide cyclization. Products range from polypeptide building blocks, intermediates to active/functional peptides and peptide derivatives (such as carnosine L-Carnosine, glutamine dipeptide, N-acetyl carnosine, Gly-His-Lys skin care peptide, etc.), and provide process development, custom synthesis, and OEM foundry (laboratory/pilot to commercial scale) for customers in the pharmaceutical, cosmetic, and food sectors. The parent company Jipeptide Biotechnology (founded in Wuhan in September 2012) has 200 acres of chemical land, 20,000 square meters of self-built plant, 4 industrialized production lines, and an annual production capacity of 1,000 tons of small molecule peptides, fully implementing GMP management.

Wuhan sqn Biotechnology Co., Ltd. claims to be a leading supplier of chemical raw materials and peptides in China, focusing on health peptides, beauty/cosmetic peptides and active raw materials. It claims to have a GMP factory and 15 years of supply experience. Its products are mainly weight loss, beauty, and anti-aging peptides (such as Smeglutide, Telpotin, GHK-Cu, Melanotan II, nad +, DSIP, SS-31, etc.). It provides OEM/ODM and customization, and relies on the global logistics network to sell to North America, Europe, Southeast Asia and other markets. Note: According to the enterprise information of the Made-in-China platform, the company is registered as a "Trading Company". It was established in 2024, with a scale of 1–49 people, a registered capital of 100,000 yuan, and no independent official domain name. It mainly conducts business through the B2B platform. Its GMP qualification and "manufacturer" positioning need to be carefully verified.

Conscientia Industrial is a core member of the Conscientia Group, headquartered in China, focusing on the R&D, manufacturing and global marketing of high-quality APIs (APIs), peptides, nutritional ingredients, cosmetic ingredients and fine chemicals. Its manufacturing facilities and products comply with international standards such as GMP and ISO, and its APIs strictly comply with USP, BP, EP, JP, KP, CP and other pharmacopoeial requirements. In the field of peptides, the company provides high-purity peptide synthesis and supply. The products cover hundreds of peptides such as α-Casozepine, AOD-9604, BPC-157, CJC-1295, GHK-Cu, GLP-1 (smectin, tilapopeptide, liraglutide, mazdopeptide, retalutide, etc.), beauty and scientific research peptides, all of which have been verified by HPLC with purity of 98% +. The supply is stable and supports rapid global shipments. It is positioned to provide peptides and raw materials for the global life science and chemical industries.

ZhuoShang Bio/ExcelBio is a GMP-certified nutraceutical manufacturer founded in 2013, located in Luoyang, Henan Province, focusing on providing one-stop OEM/ODM solutions for global brands; with 30,000 m ² of FDA-registered factories (10 production lines with an annual output value of more than $100 million), supporting a minimum order of 500 pieces. Main proteins, polypeptides and custom peptides (such as GHK-Cu, GHK-Cu powder, etc.), protein powder, gummies, capsules, beverages, etc., provide full link services from R&D, procurement, production to logistics, and hold GMP, FDA, COA, HACCP, Halal and other certifications. Note: The company's self-built official website has not been retrieved. This profile is from the Made-in-China corporate store, which is a third-party trading platform information, for reference only.

Xi 'an Huilin Biotechnology Co., Ltd. ("Xi 'an Huilin Biotechnology", established in about 2006/2012, Xi 'an, about 15 years) is committed to the field of natural raw materials, building a diversified matrix across biochemical synthesis, high content of monomers, plant-derived extracts, medicinal and food homology and large health products, and providing one-stop raw material solutions for multiple industries. In terms of polypeptides, the product center covers acetyl tetrapeptide-2, zinc pyroglutamate, etc., and also manages cosmetic/cosmetic peptide raw materials (such as acetyl hexapeptide-8, blue copper peptide, etc.). It supports both sampling and customization/mass production lines, emphasizing the traceability of the whole process of raw materials and multi-dimensional quality control. According to third-party platform information, it has ISO 9001/14001/13485, FSSC 22000, halal and other certifications.

Sichuan Tongsheng Amino Acid Co., Ltd. (established in 2003 and located in Deyang, Sichuan) is committed to the research and production of amino acids and their derivatives, polypeptides and derivatives. Its products are exported to the international markets such as the United States, the United Kingdom, Italy, France, Germany, India, and Japan. In 2011, it was awarded the title of a high-tech enterprise. In 2016, it was licensed as an academician expert workstation for the production of amino acid food additives. In strict accordance with ISO9001: 2008 and GMP management specifications, it implements USP, EP, AJI, JP and other industry standards. Its products are based on amino acids, polypeptides and derivatives.

Shenzhen Peptide Chuangsheng Technology Co., Ltd. is a pioneer supplier of high-quality active peptides (cosmetic peptides) based in Shenzhen and radiating the world. It focuses on molecular biology and AI-driven peptide structure-activity research to provide efficient, verifiable and sustainable active peptide raw material solutions for scientific research institutions, pharmaceutical groups, medical cosmetic institutions and functional skin care brands. It has a Peptide AI design system and a peptide professional-grade laboratory, with a raw material purity of 99.8% pharmaceutical grade, adopts a biological + chemical synthesis green process (zero solvent instead of DMF), and a transdermal rate of > 80%, which meets the EU ECOCERT, US FDA gras, Japan JHOSPA and other regulations; and provides customized peptide synthesis (minimum order of 100g, 3–6 weeks delivery). The product covers 100 cosmetic peptides with 9 major efficacy matrices (blue copper peptide GHK-Cu, acetylhexapeptide-8/aquirelin, palmitoyl pentapeptide-4, conopeptide, etc.), 100% made in China, and serves 100 + customers worldwide (European pharmaceutical giant, North American pure beauty brand, CJK head beauty group).

Sichuan Pengting Technology Co., Ltd. (founded in 2021, Sichuan) is positioned as a core value creator in the global peptide industry chain, focusing on the research and development, customization and industrial-scale production of high-value APIs and cosmetic peptides. Integrated supply chain and 6,500 ㎡ co-production base, products cover metabolic APIs (Tirzepatide, Semaglutide, Retatrutide, etc.) and popular cosmetic raw materials (GHK-Cu blue copper peptide, Melanotan-II, etc.). With ISO/GMP dual certification, we can provide a full set of DMF, COA and MSDS documents. The R&D team includes 5 + PhDs, and has industrialized more than 100 effective raw materials. We support 50g trial orders to tonnage commercial supply, with a delivery period of 15–30 days. Customers cover biotechnology innovation pharmaceutical companies, CDMOs, cosmetic brands and scientific research institutions in North America, Europe and Asia.

Shenzhen Xingkaiyue Biotechnology Co., Ltd. (established in 2020, Shenzhen) official website "About Us" positions it as a comprehensive technology enterprise integrating R&D, production and sales, mainly engaged in fine chemicals, chemical synthetic raw materials, pharmaceutical intermediates, chemical preservatives, fragrances, food additives, etc. The company profile on the official website does not take peptides/peptide APIs as the core business direction (third-party platforms show that they also deal in oat peptides, silk amino acids and other cosmetic raw materials), and the overall trade is mainly in fine chemicals and pharmaceutical intermediates.

Founded in 2018, it focuses on the European, American, Indian, and African markets, and supports Paypal, Western Union, and Bitcoin payments.

Shanghai QYAOBIO Co., Ltd. (ChinaPeptides/QYAOBIO), founded in October 2008, is a technology-based enterprise focusing on peptide synthesis, protein expression, and antibody preparation. In China, peptide solid phase synthesis (SPPs) technology was adopted earlier. The company maturely mastered 300 + peptide special modification core technologies, and has branches and scientific research laboratories in Suzhou, Wuhan, and Ezhou; cumulatively serving more than 50,000 customers worldwide, covering more than 50 countries and China's Hong Kong, Macao, and Taiwan regions, of which more than 90% are biomedical research institutions and pharmaceutical companies such as universities, hospitals, laboratories, and research institutes. Has passed ISO 9001: 2015 quality system certification, > 99% peptide synthesis success rate, provide HPLC/MS report and optional endotoxin/salt type test, as soon as 3 days delivery; core business is peptide synthesis, protein expression and antibody preparation.

Shanghai Bootech Biotechnology Co., Ltd. (registered as "Bootech" on the official website, and the user is recorded as "Botech") was founded in 2003 and is a technology company specializing in the synthesis of peptides and the sale of supporting reagents. The company relies on and absorbs international advanced technology, has advanced synthesis and purification equipment, and develops a complete set of peptide synthesis routes, which can provide peptide products of various sizes and requirements (mg to kg). Each polypeptide is accompanied by HPLC analysis and mass spectrometry identification report. Provided by a number of senior researchers/professors to provide process guidance, long-term cooperation with domestic and foreign pharmaceutical companies and scientific research institutions to provide high-quality peptides and peptide raw materials products at a price advantage.

Founded in 2021, Motif Biotech is located in Suzhou High-tech Zone. In March 2023, the peptide R&D and production base was completed and put into production. Motif Biotech is an innovative peptide CRDMO enterprise focusing on the customization, R&D, production and service of peptide-related products. Motif Biotech is committed to becoming an international platform integrating peptide scientific research and customization, drug peptide intermediates and impurity customization, peptide API production, drug peptide R&D and process development, and beauty peptide R&D and production. The factory building of Suzhou headquarters is about 4,300 square meters, with multiple R&D and production workshops, more than 100 synthesis/purification/analysis laboratories, and a planned total annual raw material production capacity of 30 kg (powder). The GMP workshop was designed and constructed according to ich Q7, and obtained the Pharmaceutical Manufacturing License in October 2024. The production and quality meet the requirements of FDA, EMA, and NMPA. The telpopeptide API was successfully registered with the FDA in January 2025 (DMF filing). With a complex long-acting peptide modification and optimization service platform, it can produce more than 95% of customized synthetic peptide types on the market; provide full-process peptide CDMO/CMC services from drug screening (SAR), preclinical CMC, clinical samples to registration support, as well as CRO, CMO, and beauty peptide one-stop services. We have accumulated more than 35 years of industry cooperation experience, more than 1,000 cooperative customers, and 2 production bases.

Active spot merchants on B2B platforms, sending overseas directly in small batches

Hefei HeSheng Biotechnology Co., Ltd. was established in 2014 and is located in Hefei High-tech Zone. It is an innovative polypeptide biotechnology company with polypeptide technology as its core. It focuses on the customization, research and development, production and service of polypeptide-related products, and is committed to becoming an international polypeptide CRDMO integrating polypeptide scientific research and customization, drug polypeptide intermediates and impurity customization, peptide API production, drug polypeptide research and development and process development, and beauty polypeptide research and development and production. The factory area of the company is about 4,000 square meters, and there are polypeptide R&D and production workshops such as synthesis, purification and analysis, with a total planned annual raw material production capacity of 200 kg (powder). It has more than 100 patents (including 24 invention patents). The service covers research custom polypeptide synthesis (long peptide, difficult peptide, branch peptide), labeling (isotope, fluorescence), cyclic peptide (amide ring, disulfide ring, subscription peptide ring, thioether ring), modification (glycopeptide, phosphorylation, peg, etc.), deuterated service, and polypeptide drug impurity customization; GMP small test/pilot and amplification production (mg to kg grade) can be carried out.

Founded in 2014, Hangzhou Go Top Peptide Co., Ltd. (Go Top Peptide) is a national high-tech enterprise focusing on the R&D and production of polypeptides and related derivatives. It is the governing unit of the polypeptide branch of the China Biochemical Pharmaceutical Industry Association. The company has more than 4,000 square meters of polypeptide research and development center in Hangzhou, and has established two commercial polypeptide production bases in Shangyu and Anji, Zhejiang. It has a number of polypeptide production lines, large-scale polypeptide synthesis equipment, imported HPLC analysis and preparation equipment, and is equipped with a GMP standard clean laboratory. It has passed ISO9001: 2015 quality management system certification. Provides peptide customization, modification, catalogue peptides and scientific/pharmaceutical peptide products.

1688 spot order supplier, suitable for trial order purchase

Sinopep-Allsino Biopharmaceutical is a global supplier of commercial grade APIs and a full range of polypeptide/oligonucleotide CDMOs. Providing end-to-end CMC development and cGMP production from early R&D to commercialization for new drugs (NCE) and innovative pharmaceutical companies since 2009. The company's current production capacity of polypeptides is about 20–30 tons/year. It has built a large-scale GMP oligonucleotide (ASO, siRNA and GalNAc, AOC, liposome and other conjugates) production facility that can produce thousands of kilograms per year in Lianyungang, Jiangsu Province. At the same time, it has small molecule generic drugs and NCE commercial production capacity. The quality and regulatory system is mature. It has passed four FDA on-site inspections, strictly follows FDA and ich guidelines, and provides process development, analytical method development and verification, stability research, and global IND/NDA declaration support.